10mm x 5mm stone in the middle of the ureter, part of the can be discharged down, such as can not be successfully discharged, need to do further treatment under the guidance of clinicians. 10mm x 5mm stones are relatively large, stones in the ureter in the middle, you can first drink more water, appropriate exercise, observation of stone discharge, part of the stone with daily regulation can be discharged; if the stone can not be discharged, need to do further treatment, most cases need to be through extracorporeal ultrasonic lithotripsy or ureteroscopic lithotripsy and other ways of treatment. In the whole process of expulsion, once there is obvious back pain, hematuria, need to consult a doctor in time, under the guidance of the clinician to carry out standardized treatment, to avoid causing delays in the condition.