Gout patients can take sodium bicarbonate tablets for a long time, sodium bicarbonate tablets have the effect of alkalizing urine, which is beneficial for the treatment of gout. Gout is a crystal-associated arthritis caused by hyperuricemia, the specific pathogenesis is not very clear, mainly seen in men and postmenopausal women. The typical manifestations are redness, swelling, heat, pain and dysfunction of the first metatarsophalangeal joint, as well as swelling and pain in other areas such as the ankle, knee and hand joints, and some patients may also have gout stones. Since the basis of gout is hyperuricemia, keeping blood uric acid within the target range is the key to treatment. In addition to a strict low purine diet, long-term treatment with uric acid-lowering drugs is recommended, generally more commonly used are febuxostat and benzbromarone, which is often combined with sodium bicarbonate tablets.