What are the conditions of infertility caused by uterine fibroids?

  Uterine fibroids are the most common solid benign tumors in the female genital canal. Uterine fibroids are formed by the proliferation of smooth muscle tissue and are most common in the 30-40 age group, and can grow singly or multiple times and vary in size. The cause of uterine fibroids is not known, but most believe it is related to excessive estrogen stimulation in the body. The incidence of infertility in patients with uterine fibroids is about 22 to 32%, with the highest incidence of infertility in submucosal fibroids. Uterine fibroids can be classified into subplasmic fibroids, interstitial fibroids, submucosal fibroids, cervical fibroids, and ligamentous fibroids according to their sites of occurrence. Small or solitary subplasmic and interstitial fibroids usually do not affect conception or pregnancy.  Fertility due to fibroids can be caused by the following conditions: 1. Larger fibroids can deform the uterine cavity, which is not conducive to the passage of sperm, as well as the fertilization of the egg and fetal development.  2. Fibroids growing near the uterine horns can compress the opening of the fallopian tubes and cause obstruction.  3. Myomas growing in the ligament of the runner can cause elongation and distortion of the fallopian tubes on their surface, squeezing the lumen and affecting their patency, or distorting the ovaries and widening the distance between the ovaries and the fallopian tubes, preventing the egg collection function of the umbrella end of the fallopian tubes.  4. Uterine fibroids growing in the cervix may compress the cervical canal. It may obstruct the passage or change the orientation of the cervical opening away from the seminal pool in the posterior fornix, which is not conducive to the entry of sperm into the cervical opening.  5. The submucosal fibroids growing in the uterine cavity are like a spherical intrauterine device placed in the uterine cavity, which hinders fertility. The ischemia, necrosis and atrophy of the endometrium on the surface of the uterine cavity are also detrimental to the fertilization of the egg.  6. Uterine fibroids may cause the frequency, amplitude and duration of uterine contractions to be higher than the normal baseline, interfering with fertilization of the egg or miscarriage after implantation.