You can take sildenafil with amoxicillin, but it is recommended to take it at intervals of more than half an hour and not to take two drugs at the same time. Amoxicillin is a broad-spectrum beta-lactam antibiotic used to treat inflammatory infections caused by sensitive bacteria, such as hemolytic streptococcus and streptococcus pneumoniae. Sildenafil is clinically used to treat erectile dysfunction in men, and the drug reacts with ibuprofen, ritonavir and other drug components that do not contain amoxicillin, so it is possible to take amoxicillin and take sildenafil at the same time. After taking amoxicillin and sildenafil need to pay attention to the contraindications of the drug, it should be taken under the guidance of a doctor, and the two drugs should be taken more than half an hour apart. Taking medication should first understand the knowledge of the use of medication, the need to consult a doctor before using the drug, to understand the contraindications of the use of medication.