What to do about myelosuppression after the first chemotherapy

Post-chemotherapy myelosuppression can be categorized into four degrees and requires different management depending on the degree of myelosuppression. 1. The grades of post-chemotherapy myelosuppression include: (1) Grade I: hemoglobin 109-95g/L, neutrophils 1.9-1.5*10^9/L, platelets 99-75*10^9/L; (2) Degree II: hemoglobin 94-80 g/L, neutrophils 1.4-1.0*10^9/L, platelets 74-50*10^9/L; (3) Degree III: hemoglobin 79-65 g/L, neutrophils 0.9-0.5*10^9/L, platelets 49-25*10^9/L. (4) Degree IV: hemoglobin <65 g/L, neutrophils <0.5*10^9/L, platelets <25*10^9/L. 2. Bone marrow suppression requires treatment to improve anemia, elevate white blood cells and platelets, and there are different treatments for different degrees of bone marrow suppression. (1) Improvement of anemia: subcutaneous injection of erythropoietin is necessary for degrees I and II, and iron, folic acid and vitamin B12 can be given at the same time. Ⅲ, Ⅳdegree should be timely transfusion of red blood cells to improve the symptoms. (2) Raise leukocytes: no medication is needed for I degree, recombinant human granulocyte colony-stimulating factor (G-CSF) is used for II degree in accordance with the opinion of the specialist, and G-CSF should be applied for III and IV degree under the guidance of the specialist. (3) Platelet elevation: reduce strenuous activities to avoid injury and bleeding for I and II degree, subcutaneous injection of recombinant human thrombopoietin for III degree, and platelet transfusion for IV degree.