If a child coughs at 1-3 am, the following measures can be used to deal with it. First of all, give children timely application of bronchodilator drugs to relieve, because some children 1-3 am cough, is due to suffering from cough variant asthma caused by symptoms. Children at this time of the day often have a cough that takes longer to heal than 4 weeks, and the cough is dry and sputum-poor, especially during the daytime when the cough is aggravated by exercise. Children often have a history of eczema and allergic rhinitis, which can be treated with nebulized inhalation therapy with Bolivarconi. Secondly, erythromycin is applied to children for treatment, because some children’s 1-3 am cough is due to mycoplasma infection, and the application of erythromycin can have a good therapeutic effect.