Acne is a chronic inflammatory skin disease that involves hair follicles and sebaceous glands. It can affect people of all ages, but the incidence is higher in adolescents. The earliest typical lesions are pimples located at the mouth of the hair follicle, divided into two types of whiteheads and blackheads, during the development of inflammatory papules, pustules, nodules, abscesses, cysts, easy to form hyperpigmentation, enlarged pores and even scar-like damage. It affects beauty and can lead to disfigurement in serious cases, causing great psychological stress and mental anguish to young people. Early detection and early treatment of this disease is important. Timely and standardized diagnosis and treatment can avoid or reduce the damage to the skin. The current principles of Western medical treatment for acne are: debridement, dissolution of keratin, sterilization and anti-inflammation. Commonly used drugs include antibiotics, vitamin A, estrogens, glucocorticoids, etc. The effectiveness of treatment varies from person to person, and long-term medication can easily lead to drug resistance and has potential toxic side effects. TCM mainly adopts evidence-based treatment, which can achieve good results, but some patients have poor compliance with long-term oral Chinese medicine. In the past treatment process, patients preferred other therapies, such as acne squeezing, drug inversion, etc., but these are all auxiliary treatments, and the use of these methods alone cannot achieve satisfactory results. Recently, a new red and blue light photodynamic acne treatment instrument was purchased by our department, bringing a boon to patients with “acne”. It is a new method of treating inflammatory acne that is safe, non-invasive and has no side effects. It is simple to treat and has remarkable efficacy. It is also certified by the U.S. Food and Drug Administration (FDA) as the most powerful, safe and effective non-invasive treatment method available today. The instrument makes full use of the photodynamic treatment mechanism, combining blue light and red light, in which almost all the energy of high-purity blue light effectively acts on the target target – Propionibacterium acnes (the main causative organism of acne). By applying the photodynamic treatment principle, the endogenous production of the photosensitizer porphyrins by Propionibacterium acnes is activated by 417nm blue light (the main component of porphyrins is porphyrin III) to produce a phototoxic environment, which is converted into toxic monomorphic oxygen to rapidly kill Propionibacterium acnes, achieving a good therapeutic effect without generating drug resistance or causing damage to normal tissues. While red light effectively kills Propionibacterium acnes using photodynamic effects, the penetration depth is significantly higher than that of blue light, which has a stronger anti-inflammatory effect and can also stretch blood vessels, promote blood circulation, and boost metabolism to eliminate acne marks. The treatment method is simple, only need to cleanse the face after blue or red light irradiation, each time 20 minutes, 1 week 2 times, 4 weeks a total of 8 times for a course of treatment. Through the effective integration of the two methods in clinical work, it not only quickly eliminates inflammatory lesions and significantly reduces the recurrence rate, but also eliminates acne marks to make the skin soft and smooth, fully satisfying the majority of “acne” patients’ pursuit of beauty. In conclusion, the red and blue light acne treatment instrument is easy to operate, has a short course of treatment, quick results, low recurrence rate, no recovery time, and no side effects caused by oral and applied medications, making up for the shortcomings of drug therapy for acne.