If a patient has anxiety, tension and rapid weight loss, first of all, we should exclude organic or somatic diseases that cause rapid weight loss, tension and anxiety, such as cardiovascular diseases, hyperthyroidism, hypothyroidism and some tumor problems, which may cause patients to have anxiety, tension and rapid weight loss. The differential diagnosis can be made through general physical examination, neurological examination, laboratory and instrumental examinations, as well as medical history and other symptoms. If organic causes and physical diseases are excluded, the patient may suffer from functional psychiatric disorders, such as schizophrenia and phobias, which may be more serious, such as hallucinations or delusions of victimization, and the patient is under extreme stress and fear for a long time, such as motor restlessness, and then there is a significant decrease in appetite and poor sleep. This time, we should use some antipsychotic drugs, such as olanzapine, quetiapine; some anti-anxiety drugs, such as diazepam, alprazolam; and some antidepressants, such as paroxetine, citalopram, etc.