Pain in the middle of the abdomen can be caused by a variety of factors such as prostatitis in men, uterine fibroids in women, or urinary tract infections. 1. Prostatitis: Prostatitis is caused by pathogen infection or other reasons, alcoholism, spicy diet, sedentary and so on may induce prostatitis. It can manifest as abdominal pain, urinary frequency, urinary urgency, urinary pain, urinary incontinence and other symptoms. It can be treated with antibacterial drugs under the guidance of a doctor. 2. Uterine fibroids: it may be related to genetic susceptibility, sex hormone level, stem cell dysfunction, and may manifest as abdominal swelling, pain, increased menstrual flow, leukorrhea, dysmenorrhea and other symptoms. 3. Urinary tract infection: it is the basic of urinary tract infection caused by pathogenic microorganisms, which can be hidden pain or tingling in the middle of the abdomen, often accompanied by frequent urination, urgency, painful urination, and even accompanied by fever, accompanied by hematuria. Can be under the guidance of the doctor for anti-infection treatment. The appearance of pain in the middle of the abdomen, timely to the hospital, through the relevant examination, clear cause, and then targeted treatment.