Patient: 4-5 years, dizziness, numbness in hands and feet, weakness, taking anti-thirst pills, rice arrival, Glipizide tablets, but not effective, what is the best medicine to take? What can’t I take? BC 8.4 before meals, 19.4 after meals. Wang Jianbin, Department of Internal Medicine, Eye Hospital of the Chinese Academy of Traditional Chinese Medicine: Check your insulin level at the hospital to determine, generally adults are mostly type 2 diabetes, from the analysis of your symptoms you may have diabetes for more than 5 years, complicated by peripheral neuropathy, so there is numbness in the hands and feet, poor control of blood sugar feeling dizzy and weak. You need to do electrocardiogram, urine routine, liver and kidney function, blood lipid and fundus examination to understand whether there are any comorbidities and complications, control diet, moderate exercise, blood sugar control target is 6-7 fasting, 2 hours after meal about 10. The medication you are taking contains Eugenol (glibenclamide), which is equivalent to one tablet of Eugenol for every 10 pills, 75% of which is excreted from the kidneys, and Mepida (glipizide), which is the same type of substance. If you are overweight, you can combine metformin, and if you have a large staple diet, you can also combine bactrim. If you are not fat, or if you have fundus, heart or kidney complications or combined with liver disease, insulin is recommended, and blood glucose control is the first goal, otherwise the complications will gradually worsen to a certain extent and cannot be reversed.