The chances of conversion after cold knife conization are relatively high. Cold knife conization is a kind of surgery commonly used in gynecology to treat cervical lesions, mainly through conization of the lesions of cervical lesions, so that the human papilloma virus can be eliminated, so as to achieve the purpose of curing the disease. Under normal circumstances, the chances of a woman’s HPV infection turning negative after cold knife conization are relatively high. However, while women undergo the procedure to remove the localized cervix, they also need to pay attention to post-operative care and hygiene in daily life, adjusting bad habits, etc., which can also increase the chances of the virus turning negative. Women should avoid too much walking after the cold knife conization of the cervix, and also avoid having sex too early. Regular checkups are also needed, and if the virus is still present, the next step of treatment is needed.