The site of deep headache is in the head, and the department to which it belongs is internal medicine, neurology, and the diseases associated with it are brain abscess, headache, meningitis, hydrocephalus, meningioma, cranial fossa meningioma, and intracerebroventricular meningioma. Deep headaches are most often seen in brain abscesses, encephalitis, and brain tumors with external radiation to the ipsilateral side. Possible related symptoms are throbbing headache, convulsions, epileptic headache, dull pain, excessive dreaming, nausea, weakness, and recurrent headache. How is a deep-seated headache diagnosed? Headaches caused by intracranial lesions are more severe, mostly deep distension, blast-like pain, often accompanied by vomiting in varying degrees, signs of neurological damage, convulsions, impaired consciousness, mental abnormalities and even changes in vital signs. In intracranial tumors, the headache is mostly deep, intermittent and progressively worse, and can be aggravated by stool and coughing, and fundus examination can reveal optic papillary edema. Brain abscesses often come from direct spread of infection in the middle ear, mastoid process, and paranasal sinus, with severe headache, nausea and vomiting, and even impaired consciousness as well as systemic infection symptoms. Inflammatory headache of the meninges usually has an acute onset with persistent deep headache, accompanied by fever and vomiting.