24-hour urine protein quantitative 8000mg is more serious, for a large amount of urine protein. The normal value of 24-hour urine protein quantification is usually not more than 150mg. Urinary protein is a sign of kidney damage and a risk factor for renal decompensation, and the monitoring of proteinuria is of great significance in guiding the treatment of chronic kidney disease, evaluating the effect of treatment and judging the prognosis. According to 24-hour urine protein quantification, it is divided into three categories: mild, moderate and severe. Mild: 24-hour urine protein quantification <0.5g, moderate: 24-hour urine protein quantification 0.5-2.0g, severe: 24-hour urine protein quantification >2.0g , patients with 24-hour urine protein quantification 8000mg more serious. In this case, it is recommended to go to the regular hospital in a timely manner, under the guidance of the doctor to clarify the cause of the disease, to carry out active and effective symptomatic treatment, do not use private medication to avoid causing adverse effects, to avoid delaying the condition.