Chemotherapy without surgery for stomach cancer is suitable for patients who do not have surgical indications, but the treatment effect is not as good as that of comprehensive treatment. Under normal circumstances, early gastric cancer is only operated without chemotherapy. In the advanced stage of gastric cancer, comprehensive treatments such as surgery, chemotherapy, radiotherapy and targeted therapy are needed, which can significantly prolong the survival period of patients. If advanced gastric cancer does not have surgical indication, it can be treated with chemotherapy only without surgery, which can also inhibit the growth of tumor cells, but the therapeutic effect is obviously not as good as that of comprehensive treatment. For specific treatments, it is recommended that stomach cancer patients should listen to professional doctor’s advice and formulate effective treatment plans to effectively inhibit the growth of tumor cells and avoid further deterioration of the condition.