Brain natriuretic peptide precursor 1400 is likely to be a manifestation of heart failure. Acute heart failure is usually treated with oxygen, morphine injection and vasoactive drugs; chronic heart failure is usually treated by actively controlling the primary disease, such as diabetes mellitus and hypertension, and using some diuretics, antiplatelet agents and neuroendocrine inhibitors according to the situation. Brain natriuretic peptide precursor is a heart failure marker, as an independent prognostic indicator to determine the mortality of heart failure patients. The normal value of brain natriuretic peptide precursor is below 450pg/ml for people under 50 years of age, and below 900pg/ml for people over 50 years of age, and more than 900pg/ml suggests the possibility of heart failure. Clinically, brain natriuretic peptide levels are significantly higher in heart failure patients, and brain natriuretic peptide increases significantly 6-12 hours after the onset of acute myocardial infarction and reaches a peak 7 days later. Heart failure is categorized into acute and chronic. Acute heart failure patients are treated in the following ways: firstly, make the patient take the sitting position or semi-recumbent position, legs down, reduce the venous return of the lower limbs, let the patient inhale oxygen through the mask or nasal catheter; follow the doctor’s instructions to give morphine, diuretics, cardiac tonic, etc., through the vein; apply vasoactive drugs, such as positive inotropes, vasodilators and vasoconstrictors. Those with severe disease or even cardiogenic shock should be monitored for hemodynamics, and treatments such as intra-aortic balloon counterpulsation, mechanical ventilation support, blood purification, ventricular mechanical assist devices, and surgery can be used. The treatment of patients with chronic heart failure is generally: control and treatment of hypertension, diabetes mellitus and other causes, targeted use of antiplatelet drugs and statin lipid regulators. Eliminate heart failure triggers, control infections, correct anemia, electrolyte disorders, control arrhythmias; adjust the dosage of diuretics, nitrates, and cardiotonic agents according to the condition; and correctly use neuroendocrine inhibitors to control the development of the disease. Cerebral natriuretic peptide precursor 1400 should go to the hospital in a timely manner, complete the relevant examination and targeted treatment under the guidance of the doctor.