Whether you can take medication before vaccination depends on which kind of medication you take. For some patients with diabetes and hypertension who need to take long-term glucose-lowering and antihypertensive drugs, such as metformin and nifedipine, such drugs can be taken before vaccination. And immunosuppressants, antiviral drugs, antipyretic analgesics, etc. are not recommended to be taken before vaccination. 1. Immunosuppressants: such as methotrexate, cyclophosphamide, azathioprine, etc., and hormones such as methylprednisolone and dexamethasone are not recommended to be taken before vaccination. This is because such drugs may affect the immune function of the body and increase the incidence of adverse reactions after vaccination. It is recommended that the patient’s condition be controlled and stabilized, and that the vaccine be administered after 1-3 months of drug withdrawal. 2. Antiviral drugs: such as amantadine, acyclovir, ribavirin, etc. Because most of the vaccines are made of viruses after attenuated or inactivated, taking such drugs before vaccination will reduce the body’s immune response to the vaccine and affect the effectiveness of the vaccine; 3. Antipyretic and analgesic drugs: such as aspirin, acetaminophen, indomethacin and other non-steroidal anti-inflammatory drugs, such drugs may reduce the body’s immune response. Before vaccination, if you have a cold and fever and need to apply such drugs, it is recommended to suspend vaccination and wait until you are cured and stop taking the drugs. For people who are taking certain medications before vaccination, if you are not sure whether you can take the medication and then have the vaccination, it is recommended to consult with the health care provider in charge of vaccination.