A 16-year-old boy with a long beard is usually caused by physiological factors, but may also be Cushing’s syndrome and other diseases. Physiological factors do not require special treatment or can be shaved off with a razor; diseases caused by factors need to be examined and treated under the guidance of a doctor. 1. Physiological factors: 16-year-old boys are in puberty, androgen increase will lead to beard growth, mild symptoms do not need special treatment, more beard can be considered to use a razor to shave. 2. Disease factors: Cushing’s syndrome can have hairy symptoms, at the same time there can be full moon face, centripetal obesity, acne, purple lines and other symptoms, need to be examined and treated under the guidance of a doctor. Appearance of long beard 16-year-old boys is usually normal, if any other discomfort is recommended to go to the hospital.