Since 1947, when American scholars Spiegel and Wycis designed the first human stereotactic instrument: the Horsley-Clarke instrument, and completed the first stereotactic surgery on a patient (dorsal thalamic nucleus destruction), advanced imaging development and the update of the instrument have played an increasingly important role in the field of neurosurgery in recent years. Not only does it provide a reliable biopsy diagnostic tool for some difficult neurological diseases but it can also treat many conditions that are difficult to solve with open surgery and gradually becomes an important part of the development of microinvasive surgery. Stereotactic neurosurgery uses imaging localization (CT, MRI or DSA) and stereotactic guidance to place puncture needles, microelectrodes and other microscopic instruments into specific target points in the brain to diagnose and treat various conditions of the central nervous system by recording electrophysiology, retaining tissue specimens, producing destructive foci and removing lesions. This technique has been developed over the past 50 years, and the scope of stereotactic neurosurgery has gradually expanded to involve all branches of traditional neurosurgery and has developed into a more complete discipline. Indications for stereotactic surgery: 1. Biopsy of intracerebral lesions: including brain tumors. Inflammation. Parasites and other unexplained lesions; 2, aspiration and removal of various cystic lesions in the brain; 3, intracerebral hematoma evacuation and drainage; 4, brain abscess evacuation and injection of antibiotics; 5, intracerebral foreign body removal; 6, treatment of various functional neurosurgical diseases; 7, various treatments within the brain tumor, such as internal radiotherapy (injection of isotopes, colloid and post-device tube); 8, laser endoscopic treatment of various lesions in the brain; 9, computer-assisted stereotactic surgery; 10, computer-assisted stereotactic surgery. 9, computer-aided stereotactic surgery; 10, stereotactic radiosurgery for various intracerebral lesions such as AVM; 11, stereotactic neural tissue intracerebral transplantation; 12, stereotactic implantation of microelectrodes (DBS, Parkinson’s, epilepsy, etc.). 13, various functional neurosurgical diseases: (1) tremor palsy, Parkinson’s disease, Parkinson’s syndrome; (2) torsional spasm, clinically characterized by dystonia and violent and involuntary twisting of the trunk of the limbs and even the whole body; (3) spastic slant neck is caused by disorders of complex physiological processes controlling head movements, in which striatal damage is predominant; (4) chronic progressive chorea, which is (4) chronic progressive chorea, a genetic disorder characterized by chronic progressive chorea-like movements and dementia; (5) psychiatric disorders; (6) epilepsy; (7) pain; (8) other cerebral palsy, mainly hemiplegia with spasticity. Stereotactic-guided surgery is precise and can be positioned in a precise 1 mm range; the surgery is less traumatic, painless and basically non-bleeding; the diameter of the surgical entry hole is about 5 mm, and the whole procedure is performed in a completely awake state, making it a truly painless and minimally invasive surgery.