The location of gout in the big toe is commonly found where the big toe joins the ball of the foot. That is, the first metatarsophalangeal joint is most common. Gout is a disease caused by elevated levels of uric acid in the blood, which causes urate crystals to be deposited in the joints and tissues, inducing localized inflammation and tissue destruction, and ultimately pain. The most common site of attack is the first toe-metatarsal joint, and the typical symptoms are redness, burning, and significant swelling in and around the joint accompanied by severe pain. When the patient gout attack, need to use colchicine, non-steroidal anti-inflammatory drugs such as celecoxib or glucocorticoids such as hydrocortisone for pain treatment, in remission need to actively lower uric acid treatment, lower uric acid drugs are mainly benzbromarone, allopurinol, etc., the above drugs need to be used under the guidance of a doctor. When the patient suffers from gout, need to pay attention to diet control, limit the intake of high-purine foods such as animal offal and seafood, usually need to drink more water, avoid drinking cola, fruit juice and other sugary drinks, and regularly to the hospital for follow-up testing of blood uric acid levels. It is recommended that gout patients go to the hospital in a timely manner to avoid delaying their condition.