The itching of the male urethral opening suggests that it is caused by infection with pathogenic bacteria. Clinically, through the analysis of a large number of cases, it is found that the following conditions lead to itching in the male urethra is more common: 1. non-gonococcal urethritis, which is caused by mycoplasma chlamydia infection, the clinical manifestations are itching in the urethra, accompanied by a burning sensation, and at the same time, a thin discharge is seen in the urethra. The patient may experience itching and pain in the urethra, accompanied by a large amount of yellow pus from the urethra, and serious patients may also have systemic symptoms, such as fever, etc. It is recommended that a gonococcal smear of the secretion be performed to clarify the diagnosis. 3. Non-specific bacterial infections The actual UTI, commonly caused by Escherichia coli or Staphylococcus aureus infections, can cause itching of the urethra with frequent and urgent urination, so early detection and early treatment is necessary.