Preparation for pregnancy folic acid is usually consumed 0.4 mg, if the ability to metabolize folic acid is medium-high risk, supplementation of 0.8 mg of folic acid, and if there is a previous history of pregnancy with a fetus with neural tube defects, supplementation of 5 mg of folic acid is recommended. Healthy women of childbearing age who are planning to become pregnant need to start folic acid supplementation as early as three months in advance. You can directly take the folic acid tablets available on the market at 0.4mg a piece, one tablet a day can replenish the required folic acid. If the folic acid folate metabolism ability test is medium-high risk, supplement 0.8mg of folic acid, and if there is a previous history of pregnancy with a fetus with neural tube defects, supplement 5mg of folic acid is recommended. Prophylactic administration of folic acid tablets during preparation and pregnancy can effectively reduce the chance of fetal neural tube malformations and reduce fetal anencephaly, spina bifida and other malformations. Oral folic acid tablets generally have fewer adverse reactions, with occasional allergic reactions, and gastrointestinal symptoms such as nausea and bloating can occur with long-term use.