Early prostate cancer is usually asymptomatic, but when the tumor invades or obstructs the urethra or bladder neck, symptoms similar to lower urinary tract obstruction or irritation may occur, and in severe cases, acute urinary retention, hematuria, and urinary incontinence may occur. Bone metastasis will cause bone pain, pathological fracture, anemia, spinal cord compression leading to lower limb paralysis, etc. In China, experts have reached a consensus that routine PSA and rectal examinations should be performed for men over 50 years of age with lower urinary tract symptoms (including urinary frequency, urgency, painful urination, hematuria, and urinary retention), and for men with a family history of prostate cancer, regular examinations and follow-ups should begin at age 45. Men with abnormal rectal examinations, clinical signs (e.g. bone pain, fractures, etc.) or imaging abnormalities should undergo PSA examinations.