The diagnosis of acute glomerulonephritis mainly includes clinical manifestations and laboratory tests. 1. Clinical manifestations: typical patients show acute nephritis syndrome, and acute kidney injury can occur in severe cases. Patients usually have glomerulonephritic hematuria, and about 30% of them have microscopic hematuria. It may be accompanied by mild or moderate proteinuria, and a few may have proteinuria in the range of nephrotic syndrome. Most patients may have morning eyelid and lower limb edema, and may have transient hypertension. 2. Laboratory tests: serum C3 and total complement decreased, and gradually returned to normal within 8 weeks, which is of diagnostic significance for this disease; patient’s serum anti-streptococcal hemolysin “0” titer increased, suggesting that there has been a streptococcal infection in the recent past; if the blood creatinine continues to rise or the condition has not improved in 2 months, timely renal puncture biopsy should be done for a definitive diagnosis. If you are suspected of acute glomerulonephritis, it is recommended that you go to a regular hospital in time, complete the relevant examinations under the guidance of a professional doctor, and receive standardized treatment.