The baby woke up crying several times in the middle of the night can be caused by many factors, such as dietary, emotional, nutritional and so on. 1. Diet: If the baby does not eat enough before going to bed, it will cause the baby to wake up in the middle of the night hungry and crying. If your baby eats too much before going to bed, it will cause bloating due to indigestion, which will cause your baby to cry many times in the middle of the night. 2. Emotional: If the baby is over-excited or frightened during the day, it will cause the excitability of the central nervous system to rise, resulting in poor sleep and restlessness. 3. Nutritional aspects: If the baby lacks vitamin D and calcium, it will cause the excitability to rise and cause the baby to wake up in the middle of the night. And calcium deficiency is often accompanied by cranial softening, occipital baldness, rib ectropion and other symptoms. The baby woke up several times in the middle of the night crying, there may be other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.