The Omicron strain refers to the Neocoronavirus B.1.1.529 variant, which is now thought to be potentially more infectious and may escape immunization. Symptoms of infection with Omicron are relatively undetectable, mainly fever, dry cough, sore throat, headache, malaise, nasal congestion, etc. Gastrointestinal symptoms such as nausea, vomiting, and diarrhea are less frequent than in those infected with the previous Neo-Crown strain, such that some infected persons are not easily detected in time. Omicron is a mutated strain of the New Crown virus, which is more infectious, more insidious and spreads faster. The Omicron variant is more likely to colonize and replicate in the upper respiratory tract, including the nasal cavity and throat, so its symptoms are mostly upper respiratory tract infections. Clinical studies have also shown that a sore throat, fever, headache, cough, and sputum are common symptoms, and the majority of infected patients are asymptomatic or mildly infected. Therefore, moderate disinfection and good personal and environmental cleanliness are needed. If there are suspected symptoms of neococcal pneumonia, such as fever, cough, shortness of breath, etc., it is necessary to monitor the body temperature and take the initiative to consult a doctor. [Note: In this article, “new coronavirus pneumonia” and “new coronavirus pneumonia” were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.