In general, normal male uric acid within 420mg / L, female uric acid within 360mg / L, 700mg / L more serious. Uric acid is the end product of purine metabolism, purine oxidation is mainly discharged with the urine, the main reason for high uric acid is because of the consumption of food containing high purine, and the body of purine metabolism problems, or impaired renal function, uric acid can not be excreted normally, if the uric acid is too high over a long period of time, there may be gout, which affects the life. Taking anti-tuberculosis drug pyrazinamide, affecting renal function, will cause the body of urate increase, so it will be high uric acid, can induce gout attack, can appear joint pain and swelling, usually can drink more water, if necessary, take sodium bicarbonate to alkalinize the urine, to promote the excretion of uric acid. If there is a gout attack or greater than 540mg / L, you can take uric acid-lowering medication, such as allopurinol, febuxostat, the use of medication should be under the guidance of a physician or pharmacist. In daily life, we must do a good job of dietary regulation, less consumption of high purine-containing foods, such as pig liver, sheep liver, oysters, etc. 700mg/L is more serious, should be timely to the hospital to seek medical treatment, under the guidance of the doctor’s reasonable use of medication.