Foot odor and hand odor are common fungal infectious diseases, which should be treated with different drugs according to different clinical types, mainly topical drugs, and systemic drug therapy according to medical prescriptions. A, topical drug treatment 1, blister type: choose less irritating cream or water treatment, such as azole cream or solution; 2, scaly keratosis type: skin without chaps can be used to exfoliate stronger preparations, such as compound benzoic acid ointment, if necessary, can be sealed; 3, impregnated erosion type: can use boric acid solution wet compresses, exudate reduced to give powder, such as zinc oxide powder, miconazole dispersion, should not choose irritating, strong exfoliating drugs. It is not advisable to choose drugs with high irritation and strong exfoliation. Second, the system of drug treatment is not effective in the external medicine, can consider the system of drug treatment, oral itraconazole or terbinafine, etc.. In case of secondary bacterial infection, antibiotics should be used in combination. Pay attention to regular rechecking of liver function during the medication period. Pay attention to personal hygiene in daily life, do not share shoes and socks, bath tubs and footbaths with others. Wear breathable and comfortable shoes and socks to keep the feet dry.