Pancreatic cancer and amylase do not have much to do with each other, and there is no necessary connection between the two, as follows: 1. Pancreatic cancer does not usually lead to abnormally elevated amylase levels, but if pancreatic cancer is accompanied by pancreatitis, it can lead to elevated amylase levels. 2. However, if pancreatic cancer is accompanied by pancreatitis, it can lead to elevated amylase level, but it is not possible to determine that pancreatic cancer must be caused by elevated amylase level. 3. In pancreatic cancer patients, some of the tumors will block the main pancreatic duct as it grows, resulting in the pancreatic juice not being able to enter into the intestines normally, and the amylase enzyme in the pancreatic juice may enter into the bloodstream, which will lead to the elevation of serum amylase enzyme. 4. There are many reasons for elevated amylase level, such as cholecystitis, pancreatitis, cholangitis, which can cause elevated amylase level due to increased bile duct pressure or increased pancreatic duct pressure. The observation index of pancreatic cancer is mainly the tumor marker check antigen 199, and also with the imaging examination to confirm the diagnosis, such as color ultrasound, CT, MRI and so on. Pancreatic cancer is a more serious disease, once found need to consult the doctor in time, do not be negligent, so as not to delay the condition.