No more than how many milliliters of pericardial effusion, meaning no more than how much is aspirated for the first time, should not normally exceed 100 ml.
Under normal circumstances, there will be 15-50 ml of pericardial fluid in the pericardial cavity, which plays a lubricating role. If the patient has a tumor disease, infectious disease and other conditions will lead to an increase in pericardial fluid, need to be aspirated. In the first aspiration, the volume of aspiration should be within 100 ml, and then the volume of aspiration can be gradually increased, and each subsequent aspiration should not exceed 300-500 ml.
In the case of pericardial effusion, the first aspiration of more than 100 ml may lead to the development of pulmonary edema. Therefore, when pericardial effusion aspiration is performed for the first time, it is important to control the aspiration volume, which should not exceed 100 ml, and the aspiration speed should be slow. If the patient experiences discomfort, or if blood is aspirated, it should be stopped immediately.