There are two possibilities for itching in the female urethra, one may be inflammation of the female urethra, which is caused by bacterial infection, this condition has urethral itching and the urethral opening may be red and swollen. The other condition may have mycosis vaginalis, where the discharge of vaginal fluid with the presence of mycobacteria causes itching at the urethra, and in this case the mycobacteria can be found by taking the vaginal discharge for examination. It is recommended that the first thing you should do is to treat the mycosis fungoides and wash it locally every day, which will soon be relieved by such treatment. Bacterial infections should be treated with antibacterial agents, while mycotic infections should not be treated with antibacterial agents.