Whether hepatitis B 4.5 positive is dangerous or not depends on the patient’s personal situation, these two positive items indicate that the patient may be in the period of infection or in the stage of recovery. Among the five tests of hepatitis B, the fourth and fifth tests are hepatitis B e antibody and hepatitis B core antibody, generally speaking, if these two tests are positive, it means that the patient is in the period of infection or in the stage of recovery, if the patient wants to know more about his/her situation, he/she can carry out the quantitative test of hepatitis B DNA and liver function test. Hepatitis B 4.5 positive test results alone can not accurately determine the disease, but also need to be combined with the characteristics of the medical history, other test results to make an accurate judgment, it is recommended that the cause of the disease should be clarified under the guidance of the doctor.