If the patient has itchy skin during infusion, it is usually due to the following factors: 1. Certain allergic reaction occurs during infusion, for example, if the patient has a history of allergy to cephalosporin, penicillin and other drugs, even if the skin test reaction is negative, if the infusion speed is too fast or chronic allergy occurs, itchy skin also occurs in the course of the infusion. 2. If there is a small amount of pathogenic microorganisms in the fluid or there is a re-infection of bacteria or viruses, there will be itching and rash during infusion.3. If the speed of infusion is too fast or the dosage and concentration of the drugs are too large, there will be itching on the body and skin during infusion.4. If the patient has a history of allergic reaction to the drugs or there is a certain allergic reaction and cross-reactivity between the drug and other drugs, there will be a certain allergic reaction and cross-reactivity during the infusion. If the patient has a history of drug allergy, or the application of drugs and other drugs, there is a certain allergic reaction and cross-reaction, will also appear in the infusion of itchy skin.