Blackheads usually refer to mild acne, and blackhead removal can be done with medications such as retinoic acid cream, adapalene gel, and salicylic acid ointment. If blackheads are not combined with infection can be treated with medications such as retinoic acid cream, adapalene gel, salicylic acid ointment, etc. to promote the dissolution and discharge of blackheads and pimples; Benzoyl peroxide, azelaic acid and other medications have the ability to inhibit or kill Propionibacterium acnes, which is a second line of medication for blackheads; when there is infection can be considered the use of clindamycin, erythromycin, and other topical antibiotic preparations for treatment. These drugs may cause erythema, dryness, itching and other adverse reactions, mostly mild and moderate reactions, if the adverse reactions are serious should reduce the number of times the drug is used, or seek medical advice. It is recommended that patients with blackheads seek medical attention in a timely manner, standardize treatment under the guidance of a doctor, and avoid private medication to avoid delaying the condition. Patients can use warm water to wash their face in daily life, keep their face clean, do not use oily cosmetics, and avoid eating spicy, stimulating and greasy food.