Children with fever caused by bacteria, if the temperature is over 38.5 ℃, it is usually recommended to take antipyretic drugs and antibiotics such as beta-lactams, macrolides and other drugs. 1. Antipyretic drugs: Children with fever caused by bacteria can be treated with antipyretic drugs such as ibuprofen or acetaminophen if their temperature is above 38.5℃. 2. β-lactams: β-lactams are commonly used drugs such as penicillin, cefixime, etc. These antibiotics have strong antibacterial activity and fewer side effects, less impact on liver and kidney function, safer and more effective. 3. Macrolides: If the child is allergic to β-lactam drugs, you can also choose macrolide drugs, such as azithromycin, which is easier to take, antibacterial activity is stronger, so it is more widely used. Children with fever caused by bacteria, it is recommended to consult a doctor in a timely manner, all of the above medications need to be used under the guidance of a doctor, avoid self-medication.