He loves to study but is extremely inefficient, and every time he takes an exam, he basically “competes” with a few other people whose expertise is not consolidated to be in the bottom He is a keen but inefficient student. In addition to his academic performance, Bill had his own troubles. He had a signature habit known throughout the university – coughing and clearing his throat, coughing everywhere he went, often hearing his voice before seeing him. After four years of college, almost everyone in the university was familiar with Bill’s signature, especially after meals and when lying down, Bill’s coughing and throat-clearing became more obvious, and several of his dorm mates jokingly called Bill’s coughing a lullaby before bed. In addition to coughing and throat clearing, Bill often felt a foreign body in his throat, and almost every day he brushed his teeth with nausea and vomiting, sometimes with chest tightness and shortness of breath, and occasionally with heartburn and belching. After numerous visits to doctors in the department of quintuplegia and respiratory medicine, and repeated chest X-ray and laryngoscopy examinations, the conclusion was mostly chronic pharyngitis, and he had taken a variety of antibacterial drugs, anti-inflammatory drugs, cough medicine, pharyngitis medicine, etc. He also tried many secret prescriptions, but he did not get better. Bill’s academic performance and trademark cough often became the laughing stock and talking point of his classmates after tea and dinner. After graduation, at a friend’s party, there happened to be a doctor in the room, and Bill’s trademark cough caught the doctor’s attention, and he suggested that Bill should see a gastroenterologist who might be able to help. At his suggestion, Bill went to see a gastroenterologist and after some related tests, he was diagnosed with GERD pharyngitis, and the doctor prescribed him some medicine for his stomach. The clinical manifestations of chronic pharyngitis are often a foreign body feeling in the pharynx, the patient often has a cough and throat clearing action, but can not cough, can not swallow; throat easily dry, burning, itching, sometimes hoarse voice; morning brushing teeth, throat clearing or coughing easily cause nausea and vomiting. There are many clinical causes of chronic pharyngitis, and gastroesophageal reflux plays an important role in its development. Under normal circumstances, the sphincter acts as a one-way switch. When food or drinks are swallowed through the mouth and enter the lower esophageal sphincter, the switch opens and the food and drinks are discharged into the stomach. When the sphincter relaxes for various reasons and the one-way switch fails, stomach contents and gastric juice may reflux into the esophagus and even reach the pharynx and trachea, stimulating the pharynx and trachea, resulting in pharyngeal discomfort, foreign body sensation, chronic cough, etc. Especially after meals, lying down, etc., the chance of acid reflux increases significantly, and the symptoms of GERD pharyngitis become more obvious. GERD pharyngitis is also associated with reduced peristaltic capacity of the esophagus, delayed gastric emptying and increased intragastric pressure. In addition to the clinical manifestations of chronic pharyngitis, it can often be accompanied by symptoms of GERD of varying degrees, such as chest pain, heartburn, acidity, belching, gastric distention, stomach pain, etc. Barium meal and gastroscopy have little value in confirming the diagnosis. For patients with recurrent, untreated chronic pharyngitis, appropriate tests can be performed to clearly diagnose gastroesophageal reflux pharyngitis. 24-hour esophageal pH monitoring is currently the best quantitative test for gastroesophageal reflux disease, which can dynamically monitor changes in distal and proximal esophageal pH, and can also confirm the presence of acid reflux and the relationship between reflux and gastric acid. Barium meal examination and gastroscopy are not of great diagnostic value for this disease. Esophageal manometry can show lower esophageal sphincter pressure and reveal the pathologic basis of GERD. For hospitals where 24-hour esophageal pH monitoring and lower esophageal sphincter manometry cannot be routinely performed, a proton pump inhibitor treatment test can be taken for suspected cases of this disease after analyzing the patient’s medical history and clinical manifestations, and if the patient’s symptoms disappear or improve significantly, it suggests an obvious gastric acid-related disease. According to the clinical manifestations of gastroesophageal reflux pharyngitis, for those who are diagnosed with this disease, the abuse of antibacterial drugs is harmful and can be used alone or in combination with gastric acid inhibitors, such as proton pump inhibitors or H2 receptor blockers, gastroprokinetic drugs, and acid neutralizing drugs. If internal treatment is not effective, anti-reflux surgery can also be tried.