Arrhythmia combined with coronary artery disease can take the following major types of drugs: 1. Anti-arrhythmic drugs can be applied, the most commonly used drugs are beta-blockers, such as metoprolol tartrate, metoprolol succinate, etc., clinically used drugs are betalactone, but this drug has certain contraindications, for patients with acute pulmonary heart disease or chronic obstructive pulmonary disease, the application is prohibited. 2. If the arrhythmia is not significantly relieved by the application of beta-blockers, amiodarone can also be applied, which is an anti-arrhythmic drug, and the process of taking it should be tested for heart rate, blood pressure and oxygen saturation, and thyroid dysfunction should be avoided for a long time. The heart rate can also be treated with drugs such as Cediran or digoxin.