Pulpitis night pain can be relieved by physical pain relief, medication pain relief, open pulp drainage and other ways to ease the pain. 1. Physical pain relief: you can cool down the pulp by holding cool water in your mouth, or using ice cubes or ice towels to apply to the affected area, etc. There is a characteristic of endodontitis after suppuration, i.e., “hot pain, cold pain”, and after cooling down, the pain can be relieved significantly. 2. Drugs for pain relief: you can take anti-inflammatory drugs under the guidance of the doctor, such as ibuprofen extended-release capsules or aspirin tablets, etc. to temporarily relieve the pain. 3. Pulp drainage: If it is convenient to go to the hospital at night, you can go to the emergency room of the hospital in time for local anesthesia to open the pulp and pulp nerve extraction, which can relieve the pain. It is recommended that patients with endodontitis pain at night should first take physical pain relief and medication, and go to the hospital if necessary to avoid delays. The use of drugs should follow the doctor’s instructions.