Failure to see fetal heartbeat and fetal buds 28 days after implantation should mean that the embryo has stopped developing and is a premature miscarriage. Whether it is in vitro or normal conception, the presence or absence of fetal heartbeat and fetal buds is an early indicator of whether the fetus is healthy and developing. An IVF transfer is a process in which an egg and sperm are fertilized in vitro to form a fertilized egg, which is then cultured in vitro for three to five days to form an early blastocyst or a late blastocyst, and then placed into the uterine cavity for implantation into the lining of the uterus, which is the process of implantation. Twenty-eight days after implantation corresponds to 31 to 33 days of normal conception, or 45 to 47 days of menopause, which is between 6 and 7 weeks of pregnancy, when the fetal heartbeat is visible. The normal development of the embryo is analyzed according to the current blood chorionic villus hormone values and the time of implantation of the transferred embryo. The absence of fetal heart and buds should mean that the embryo has stopped developing, and it can be observed for another week and then rechecked, if the fetal heart is still not seen, then the development has generally stopped. Finally, after the implantation, you must pay attention to not be tired, and at the same time under the guidance of the doctor to take some drugs to protect the fetus, such as progesterone injection.