Betalucil, or metoprolol, can aggravate or induce coronary artery spasm, so metoprolol is generally contraindicated for coronary artery spasm. Coronary artery is a blood vessel that supplies blood to the heart muscle. Coronary artery spasm is stimulated by various factors, induced spasm of coronary artery vessels, resulting in vasoconstriction narrowing, or even occlusion, causing myocardial ischemia and hypoxia, resulting in symptoms such as chest tightness, chest pain, and clinically known as variant angina pectoris. Metoprolol, a beta-blocker, can block beta receptors, causing the heart rate to slow down and slowing down the contraction of the heart. When using β-blockers, β-receptors are blocked and α-receptors are relatively dominant, which tends to induce coronary spasm or aggravate coronary spasm, and should not be used for variant angina, but can be used for the treatment of hypertension, arrhythmia, infarction, and coronary stenotic angina. Cardiogenic shock, sick sinus syndrome, III degree atrioventricular block, etc. are prohibited. When coronary artery spasm occurs, it is recommended to promptly seek medical attention. Metoprolol may cause dizziness, headache, gastrointestinal reactions, bronchospasm and other adverse reactions, and the use of the drug needs to be under the guidance of a professional doctor. If there is any discomfort, it is recommended to go to the hospital in time for treatment.