There are no new drugs for leukemia, and the treatment is mainly symptomatic, with drugs such as non-steroidal anti-inflammatory drugs (NSAIDs), colchicine, thalidomide, and glucocorticoids. There is no recognized effective cure for leukoaraiosis, and the aim of treatment is mainly to inhibit inflammation, prevent recurrence, and slow down the progress of the disease, etc. No new drugs have emerged. Drug therapy is mainly non-steroidal anti-inflammatory drugs such as aspirin, etc. have a certain effect on joint pain. Colchicine may be effective for arthropathy and erythema nodosum. Thalidomide may be effective in mucosal ulcers. Systemic glucocorticosteroids such as prednisone and dexamethasone are used primarily to treat vasculitis of the integumentary system. Leukoaraiosis requires standardized treatment under the guidance of a doctor, and medications should be used as prescribed.