Normally, the spine stops growing when the epiphyses close. The epiphysis is a broad translucent band of cartilage between the epiphysis and metaphysis that appears on x-ray before the bone matures. Metaphyseal closure is the gradual ossification of the cartilage between the epiphysis and the metaphysis as the bones grow older, resulting in the narrowing of the epiphysis and the disappearance of the epiphysis when the cartilage is completely ossified, forming a tight seam. If the epiphysis is completely closed, the bone stops growing. The main reason for the growth of the human body is the continuous growth and division of cartilage cells, which allows the long bones to grow, and the main component of the epiphysis is cartilage. If the epiphyses are closed, height may be stable and less likely to increase. Therefore, after epiphyseal closure, the potential for natural growth is lost. Whether it is the spine or the short and long bones of the limbs, the possibility of regrowth is very small, and the height almost stops growing again.