Skull repair surgery repair materials are very important. A good material will not only improve the success rate of the surgery. And it can reduce the chances of postoperative complications. Thousands of years ago, there were doctors tried to use various materials for skull repair, limited by the backward medical knowledge and technical means at that time, there were no suitable materials for doctors to choose. With the advancement of medicine, more and more cranial repair materials have become available for use. Plexiglass, light apatite and calcium phosphate cement materials, which were once used in clinical practice, were gradually withdrawn from the medical arena due to their poor clinical results. The commonly used material for cranial repair today is titanium mesh, which is also a quality material with long-lasting application and good results. However, the metallic property of titanium mesh often brings the consequences such as sensitivity to cold and heat reactions and CT image errors to patients. A new clinical material for cranial bone repair, the material is polyether ether ketone peek material, which is a polymer biomaterial, extremely close to the human cranium in terms of elasticity, heat conduction, hardness, stability, etc. After using the three-dimensional shaping of the PEEK bone plate, it can fit perfectly with the cranial structure, without worrying about the accuracy and aesthetics of the problem. Numerous clinical cases have shown that there are currently no discomfort or complications associated with PEEK cranial repair materials, so PEEK is the better material for cranial repair.