Non-atrophic gastritis of the gastric sinus with individual glandular enterosis is mainly treated by eradicating Helicobacter pylori, lowering gastric acid, and protecting the gastric mucosa, with drugs such as omeprazole. 1.Eradication of Helicobacter pylori:Chronic inflammation of the gastric sinus with intestinal metaplasia belongs to pre-cancerous lesions, if it is clear that the infection is Helicobacter pylori, should be preferred to the quadruple therapy, the drugs include omeprazole, metronidazole, amoxicillin capsules, colloidal bismuth pectin capsule. Metronidazole adverse reactions are most common in the digestive tract, and it is contraindicated in pregnant women and lactating women. Amoxicillin is contraindicated in penicillin allergy. 2. Reduce gastric acid: oral H2 receptor antagonists such as ranitidine, or proton pump inhibitors such as omeprazole to treat. Omeprazole can cause dry mouth, mild nausea, vomiting, abdominal distension and other adverse reactions, allergic to omeprazole, severe renal insufficiency is prohibited. Ranitidine can cause nausea, rash, constipation and other adverse reactions, pregnant women, nursing women are prohibited. 3. Protect the gastric mucosa: such as aluminum sulfate, belongs to the effective anti-peptic ulcer drugs, with adsorption of pepsin and bile acids, protect the ulcer surface, and promote the role of ulcer healing. It can cause constipation, back pain, diarrhea and other adverse reactions, chronic renal insufficiency should be used with caution. In addition, patients need to avoid cold and spicy stimulating food, avoid overeating, can eat small meals, eat easily digestible food. Appearance of gastric sinus non-atrophic gastritis individual gland intestinalization, it is recommended to consult a doctor in a timely manner, the use of drugs under the guidance of the doctor, do not self-medication, so as not to cause adverse reactions.