Sepsis is caused by infection, and is related to factors such as low immunity and strong invasion of pathogenic bacteria, which may lead to serious consequences such as organ dysfunction. 1. Organism reasons: sepsis often occurs in immunity low people, mostly secondary to large burns, open fractures and other serious trauma after infection; and diabetes, uremia patients, and long-term use of drugs such as dexamethasone after infection is also prone to sepsis. 2. Pathogen factors: invasion of the body of pathogenic bacteria in large numbers, virulence is also one of the causes of sepsis, such as Staphylococcus aureus and other Gram-positive bacteria can be secreted plasma coagulase and other exotoxins, and Escherichia coli can be released endotoxin, etc., In addition, intravenous catheter infections, enteric infections, etc., is also a common infection pathway of sepsis. It is recommended to seek prompt medical attention and treatment for more serious infections without delay to avoid progression to sepsis, which is life-threatening.