Sore throat is also related to thyroid gland, especially the occupational disease of thyroid gland, the most common is nodular goiter or simple thyroid adenoma. Because of the gradual enlargement of the lesion, tracheal compression will occur, the patient will have a choking sensation when swallowing food, neck discomfort; patients with obvious tracheal compression will also have a sense of pressure, especially after activities, chest tightness and panic, ultrasound and CT examination can also find tracheal compression, and if necessary, need to choose surgical treatment. In addition, if secondary to an upper respiratory tract infection, thyroiditis may be characterized by pharyngeal pain and anterior neck pain and discomfort, accompanied by fever. Treatment should be systematic, including analgesia, and in the case of abnormal thyroid function, hypothyroidism, supplementation with exogenous thyroxine tablets, and regular monitoring of laboratory tests.