Breast nodule is a common disease in breast surgery. Bilateral symmetrical breast nodules can usually be seen in breast fibroadenoma, breast cystic hyperplasia, breast cancer and so on. 1. Breast fibroadenoma: caused by abnormal response of fibroblasts to estrogen, commonly seen in young women, is a benign tumor with nodules as the only manifestation. It is a benign tumor with nodule as the only manifestation. The main treatment method is surgery. 2. Breast cystic hyperplasia: mostly seen in middle-aged women, caused by estrogen and progesterone imbalance. The main manifestation is nodules in the breast, accompanied by periodic pain, usually related to the menstrual cycle. Commonly used treatment is symptomatic treatment, which can be applied under doctor’s guidance, such as Xiao Jin Wan and other drugs. 3. Breast cancer: there are various types, including non-invasive cancer, invasive specialized cancer and invasive non-specialized cancer. The main manifestation is painless nodules in the breast, which may have orange peel or dimple sign. The main treatment is comprehensive treatment mainly based on surgery. If there are nodules in both breasts, it is necessary to consult doctor in time and receive treatment according to doctor’s prescription after finding out the cause.