If syphilis is combined with HIV infection, there are specific treatments for syphilis that can cure it, but there is no treatment for HIV. Because syphilis is caused by infection with the syphilis spirochete, it is effective for treatment with penicillin. Depending on the course of the disease, a weekly dose of benzathine penicillin for three weeks, followed by follow-up titers, most of them can be clinically cured. In case of HIV infection, there is no specific drug to treat HIV. Now there is antiviral treatment that can make the virus very low in viability so that the infected person does not have serious clinical manifestations and needs to take antiviral drugs for a long time. Now there are reports that pregnant women with HIV can give birth to normal newborns, and these need to be controlled with long-term monitoring and medication.