The main reasons for the occurrence of peptic ulcer are as follows: 1. The most important etiology is Helicobacter pylori infection: about 90%-100% of patients with gastroduodenal bulb ulcer can be detected with HP infection, and about 80%-90% of patients with gastric ulcer can be detected with HP infection; 2. Drug factors: patients with chronic arthritis, rheumatism or rheumatoid disease, long-term use of painkillers, such as Fotarine and Nimesulide. Patients with coronary artery disease taking long-term anticoagulant drugs such as aspirin. As well as glucocorticoid drugs such as dexamethasone or prednisone have greater damage to the gastric mucosa of the digestive tract; 3. Personal dietary habits: irregular diet, overeating or eating irritating food can trigger ulcers; 4. Seasonal factors: many patients develop the disease in autumn and winter or winter and spring; 5. Feeding factors: patients with gastric ulcers usually have abdominal pain after eating, and abdominal pain can be relieved after taking medication. Patients with duodenal ulcer have pain when they are hungry and can be relieved after eating.