Urine routine normal urinary pain is caused by more reasons, common causes are interstitial cystitis, overactive bladder disease, urethral syndrome and other causes. 1. Interstitial cystitis is mainly manifested as frequent urination, urinary urgency, dysuria, burning sensation during urination, lower abdominal discomfort, and painful urination, and sometimes hematuria. Most of the patients with interstitial cystitis have normal urine routine, but may have pain in urination, in which case cystoscopy is needed. 2. Abnormal bladder activity, overactive bladder is a syndrome characterized by urinary urgency, often accompanied by frequent urination, nocturnal urination, which may or may not be accompanied by urge incontinence. The urine routine is usually normal, and some patients may have painful urination. 3. Postmenopausal women with estrogen deficiency may have urethral syndrome, which is characterized by normal urinary output but also painful urination, and can be treated with local application of estrogen. In addition, men with chronic prostatitis can also be normal urine but painful urination, caused by the phenomenon of a number of reasons, it is recommended that the patient to the hospital in time, clear the cause of the treatment under the guidance of the doctor.