Toothache may be caused by gingivitis, periodontitis and pulpitis. Depending on the cause of the disease, ibuprofen extended-release capsules, loxoprofen sodium capsules, metronidazole tablets, levofloxacin hydrochloride capsules, etc. are prescribed. However, the medication often needs to be accompanied by appropriate dental treatment in order to be cured. 1. Gingivitis: if the patient for gingivitis stimulation of the pulp nerve caused by toothache, you can take conventional oral painkillers, such as ibuprofen extended-release capsules, sodium capsules and other steroidal anti-inflammatory drugs, and with the combination of antibiotic drugs. Antibiotic drugs such as levofloxacin hydrochloride capsules. They can effectively inhibit the reproduction of pathogenic bacteria and reduce the inflammatory reaction to relieve toothache. 2. Periodontitis: Periodontitis, caused by periodontal infection, can lead to periodontal abscesses and other diseases, and in severe cases, it can spread to the pulp, resulting in toothache. The use of metronidazole and erythromycin can be prescribed to inhibit the reproduction of pathogenic bacteria and relieve pain. 3. pulpitis: pulpitis is not effective with drugs, in acute pain can use ibuprofen to temporarily relieve pain. There are many other causes of dental disease, such as dental shock, dental caries, etc., should be timely to the hospital, improve the relevant examination to determine the cause of the selection of appropriate treatment programs to avoid further development of the condition, the use of drugs need to follow the doctor’s instructions.